by Dixie Lawrence | Sep 27, 2026 | Research, Uncategorized
Gene-targeted rationale for this Polyphenol Support mix (HSA21 overexpression + downstream pathways). This is the mechanistic story used in TNI; human efficacy remains mixed (small adult EGCG trials suggested cognitive signals; a pediatric EGCG RCT did not). Green tea...
by Dixie Lawrence | Sep 27, 2026 | Research, Uncategorized
We suggest several products that, in accordance with your healthcare providers guidelines, have proven very beneficial in caring for your loved one with Down syndrome. Nutrivene D Daily Supplement Trisomy 21 overexpresses genes including SOD1, CBS, and APP. That is...
by Dixie Lawrence | Sep 27, 2026 | Research
1. Urolithin A The Cellular Target: DYRK1A is over expressed in DS. This gene is both developmental and functional. This means the disruption present in fetal development continues during the entire lifetime. Heretofore, we have had few options with regard to...
by Dixie Lawrence | Sep 27, 2026 | Research
DYRK1A (Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A) is a highly dosage-sensitive gene located on human chromosome 21q22.13, within the Down syndrome critical region. Due to the triplication of chromosome 21 in Down syndrome (DS), DYRK1A is...
by Sara Land | Nov 13, 2023 | Inspiration by Parents, Research
Clickable link to studies: Disregulation of protein trafficking in neurodegeneration Role of metal ions in the cognitive decline of Down Syndrome Down Syndrome Regression Disorder Unraveling the complexity of neurodegeneration in brain of subjects with Down Syndrome...
by Dixie Lawrence | Jul 17, 2023 | Research, Uncategorized
Trisomy 21 Research Foundation refers only to those practitioners with the best training, expertise and knowledge of Down Syndrome biochemistry. They are not employees of the Foundation, but healthcare professionals who have provided documentation that they have an...
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